⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20550342 | 0.86 | — | — | |
| SCHEMBL7877977 | 0.86 | — | — | |
| SCHEMBL1782998 | 0.76 | CHRNB2 (0.32) | — | |
| SCHEMBL466550 | 0.75 | KDM4E (0.32) | — | |
| Hydrochloric Acid SCHEMBL11301415 | 0.73 | CHKA (0.30) | — | |
| SCHEMBL13572333 | 0.70 | — | — | |
| SCHEMBL1000578 | 0.62 | — | — | |
| SCHEMBL161377 | 0.61 | — | — | |
| SCHEMBL17458664 | 0.59 | — | — | |
| SCHEMBL29465186 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250215017-A1 | TGF-ß INHIBITOR COMPOUND AND USE THEROF | MEDINNO PHARMACEUTICAL TECHNOLOGY (ZHUHAI) CO., LTD. (CN) | 2025-07-03 | — | — | US | disclosed |
| WO-2023096850-A1 | PHOSPHOINOSITIDE 3 KINASE GAMMA INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | GEODE THERAPEUTICS INC. (US) | 2023-06-01 | — | — | WO | disclosed |
| CN-106117140-A | () huperzine A method and compositions related and Therapeutic Method | 耶鲁大学 | 2016-11-16 | — | — | CN | disclosed |
| CN-103687849-B | (-) -huperzine A methods and related compositions and methods of treatment | 耶鲁大学 | 2016-08-17 | — | — | CN | disclosed |
| WO-2010151638-A1 | JNK INHIBITORS FOR USE IN TREATING SPINAL MUSCULAR ATROPHY | MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC. (US) | 2010-12-29 | — | — | WO | disclosed |
| CN-101217955-A | Bicyclic 6-alkylidene-penems as class D beta-lactamases inhibitors | WYETH CORP (US) | 2008-07-09 | — | — | CN | disclosed |
| WO-1990003789-A1 | PYRROLO[1,2-a]IMIDAZOLE AND IMIDAZO[1,2-a]PYRIDINE DERIVATIVES AND THEIR USE AS 5-LYPOXYGENASE PATHWAY INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1990-04-19 | — | — | WO | disclosed |