Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | VNN1 | O95497 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18045769 | 0.88 | RXFP1 (0.54) | RXFP1FFAR1FFAR4AURKARPS6KB1 | |
| SCHEMBL29608704 | 0.88 | RXFP1 (0.54) | RXFP1FFAR1FFAR4AURKARPS6KB1 | |
| SCHEMBL18045767 | 0.88 | RXFP1 (0.54) | RXFP1FFAR1FFAR4AURKARPS6KB1 | |
| SCHEMBL18047218 | 0.87 | RXFP1 (0.53) | RXFP1FFAR1FFAR4AURKARPS6KB1 | |
| SCHEMBL18047219 | 0.87 | RXFP1 (0.53) | RXFP1FFAR1FFAR4AURKARPS6KB1 | |
| SCHEMBL18046841 | 0.80 | PDCD1 (0.44) | FFAR1 | |
| SCHEMBL18046838 | 0.80 | PDCD1 (0.44) | FFAR1 | |
| SCHEMBL18046941 | 0.79 | VNN1 (0.51) | FFAR1VNN1LMNA | |
| SCHEMBL18046942 | 0.79 | VNN1 (0.51) | FFAR1VNN1LMNA | |
| SCHEMBL28191712 | 0.79 | FFAR1 (0.43) | FFAR1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531660-A | α cinnamide compounds and composition as HDAC8 inhibitor | 福马治疗股份有限公司 | 2018-01-02 | — | — | CN | disclosed |