Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | F7 | P08709 | 1/20 | 0.59 |
| ▸ | F3 | P13726 | 1/20 | 0.59 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.59 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.59 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.59 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.59 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.59 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.59 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665150 | 0.85 | LMNA (0.59) | LMNACYP1A2CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL5650240 | 0.85 | LMNA (0.59) | LMNACYP1A2CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL5650237 | 0.85 | LMNA (0.59) | LMNACYP1A2CYP3A4CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL4665099 | 0.83 | LMNA (0.58) | LMNACYP1A2CYP3A4CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL4666408 | 0.83 | LMNA (0.58) | LMNACYP1A2CYP3A4CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL4666411 | 0.83 | LMNA (0.58) | LMNACYP1A2CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL800635 | 0.82 | LMNA (0.69) | LMNACYP1A2CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL31703901 | 0.82 | LMNA (0.69) | LMNACYP1A2CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL27576450 | 0.79 | LMNA (0.61) | LMNACYP1A2CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL19223886 | 0.79 | LMNA (0.65) | LMNACYP1A2CYP3A4CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107548397-B | Kv1.3 inhibitors and medical uses thereof | 4SC股份公司 | 2020-12-29 | — | — | CN | disclosed |
| CN-107548396-B | Kv1.3 inhibitors and medical uses thereof | 4SC股份公司 | 2020-04-28 | — | — | CN | disclosed |
| CN-107548397-A | Kv1.3 inhibitors and medical uses thereof | 4SC股份公司 | 2018-01-05 | — | — | CN | disclosed |
| CN-107548396-A | Kv1.3 inhibitors and medical uses thereof | 4SC股份公司 | 2018-01-05 | — | — | CN | disclosed |