1,3,5-Trichlorobenzene

1,3,5-Trichlorobenzene

SCHEMBL28192425

Clc1cc(Cl)cc(Cl)c1.[NaH]

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.89
CYP3A4 P08684 2/20 0.57
TP53 P04637 2/20 0.57
ALDH1A1 P00352 3/20 0.50
TPMT P51580 1/20 0.44
HSD17B10 Q99714 2/20 0.44
RECQL P46063 1/20 0.44
LMNA P02545 1/20 0.42
CYP2A6 P11509 1/20 0.42
IDO1 P14902 2/20 0.40
AHR P35869 2/20 0.40
HTR3E A5X5Y0 1/20 0.40
HTR3B O95264 1/20 0.40
HTR3A P46098 1/20 0.40
HTR3D Q70Z44 1/20 0.40
HTR3C Q8WXA8 1/20 0.40
HPGD P15428 1/20 0.37
DEPTOR Q8TB45 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,3,5-Trichlorobenzene SCHEMBL429512 0.94
1,3,5-Trichlorobenzene SCHEMBL28291993 0.89 TSHR (0.89) TSHRCYP3A4TP53ALDH1A1TPMT
1,3,5-Trichlorobenzene SCHEMBL29043929 0.89 TSHR (0.89) TSHRCYP3A4TP53ALDH1A1TPMT
1,3,5-Trichlorobenzene SCHEMBL28436714 0.89 TSHR (0.89) TSHRCYP3A4TP53ALDH1A1TPMT
1,3,5-Trichlorobenzene SCHEMBL27259852 0.84 TSHR (0.80) TSHRCYP3A4TP53ALDH1A1TPMT
1,3,5-Trichlorobenzene SCHEMBL27419231 0.84 TSHR (0.80) TSHRCYP3A4TP53ALDH1A1TPMT
1,3,5-Trichlorobenzene SCHEMBL27944929 0.84 TSHR (0.80) TSHRCYP3A4TP53ALDH1A1TPMT
SCHEMBL463754 0.80 TSHR (0.73) TSHRCYP3A4TP53ALDH1A1TPMT
1,3,5-Trichlorobenzene SCHEMBL27538765 0.80 TSHR (0.73) TSHRCYP3A4TP53ALDH1A1TPMT
1,3,5-Trichlorobenzene SCHEMBL27517345 0.80 TSHR (0.73) TSHRCYP3A4TP53ALDH1A1TPMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107407749-A Including microcellular structure and with the retroreflective articles of improved reflectivity 沙特基础工业全球技术公司 2017-11-28 CN disclosed