Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28192575 | 0.94 | NPC1 (0.44) | POLBNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL2178165 | 0.71 | ALDH1A1 (0.53) | POLBNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL27452226 | 0.71 | ALDH1A1 (0.53) | POLBNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL844502 | 0.71 | POLB (0.47) | POLBNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL3471202 | 0.69 | SLC6A2 (0.66) | KCNH2 | |
| SCHEMBL834676 | 0.68 | NPC1 (0.47) | POLBNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL836451 | 0.68 | ALDH1A1 (0.49) | POLBNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL29940279 | 0.67 | IDO1 (0.57) | POLBNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL28286305 | 0.67 | IDO1 (0.57) | POLBNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL2037389 | 0.67 | AKR1C3 (0.55) | POLBNPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103288833-B | Imidazo-triazine and imidazopyrimidine as kinase inhibitor | 因塞特控股公司 | 2018-01-12 | — | — | CN | disclosed |