Phosphine

Phosphine

SCHEMBL28192584

NC(Cc1ccc(OP(=O)(O)O)cc1)C(=O)O.P

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.56
SLC7A5 Q01650 3/20 0.56
PTPN1 P18031 2/20 0.55
PTGS1 P23219 3/20 0.54
ALPI P09923 1/20 0.54
PKM P14618 1/20 0.54
XIAP P98170 1/20 0.54
ITGB3 P05106 1/20 0.54
ITGA2B P08514 1/20 0.54
HIF1A Q16665 5/20 0.49
CYP3A4 P08684 3/20 0.49
ALOX15 P16050 3/20 0.49
ALDH1A1 P00352 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
KDM4E B2RXH2 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
ABCB11 O95342 1/20 0.49
CHRM2 P08172 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL273663 0.98 PTPRC (0.57) PTPRCSLC7A5PTPN1PTGS1ALPI
SCHEMBL3626587 0.98 PTPRC (0.57) PTPRCSLC7A5PTPN1PTGS1ALPI
SCHEMBL1152 0.98 PTPRC (0.57) PTPRCSLC7A5PTPN1PTGS1ALPI
SCHEMBL4066744 0.98 PTPRC (0.57) PTPRCSLC7A5PTPN1PTGS1ALPI
SCHEMBL29613927 0.97 PTPRC (0.56) PTPRCSLC7A5PTPN1PTGS1ALPI
Phosphoric Acid SCHEMBL27545043 0.97 PTPRC (0.56) PTPRCSLC7A5PTPN1PTGS1ALPI
SCHEMBL19615883 0.97 PTPRC (0.56) PTPRCSLC7A5PTPN1PTGS1ALPI
Phosphoric Acid SCHEMBL3476886 0.97 PTPRC (0.56) PTPRCSLC7A5PTPN1PTGS1ALPI
SCHEMBL29567635 0.97 PTPRC (0.56) PTPRCSLC7A5PTPN1PTGS1ALPI
SCHEMBL27947556 0.97 PTPRC (0.56) PTPRCSLC7A5PTPN1PTGS1ALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107794302-A Determine method of the cancer to EGF-R ELISA magnetic target therapy reactivity 综合医院公司 2018-03-13 CN disclosed
CN-103288833-B Imidazo-triazine and imidazopyrimidine as kinase inhibitor 因塞特控股公司 2018-01-12 CN disclosed
CN-104480200-B Determine method of the cancer to EGF-R ELISA magnetic target therapy reactivity 综合医院公司 2017-12-29 CN disclosed
CN-104774931-B Determine method of the cancer to EGF-R ELISA magnetic target therapy reactivity 综合医院公司 2017-11-10 CN disclosed
CN-104774931-A Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments GEN HOSPITAL CORP 2015-07-15 CN disclosed
CN-102586431-B Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments GEN HOSPITAL CORP 2015-04-22 CN disclosed
CN-104480200-A Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments GEN HOSPITAL CORP 2015-04-01 CN disclosed