Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | ADK | P55263 | 1/20 | 0.30 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1894921 | 0.83 | — | — | |
| Pyridine SCHEMBL28095262 | 0.73 | TDP1 (0.41) | TSHRNAPRTTDP1SLC6A2SLC6A4 | |
| Pyridine SCHEMBL27908760 | 0.73 | TSHR (0.41) | TSHRNAPRTTDP1SLC6A2SLC6A4 | |
| Pyridine SCHEMBL27629170 | 0.73 | TSHR (0.41) | TSHRNAPRTTDP1SLC6A2SLC6A4 | |
| Pyridine SCHEMBL15263781 | 0.73 | TSHR (0.41) | TSHRNAPRTTDP1SLC6A2SLC6A4 | |
| Pyridine SCHEMBL28270231 | 0.73 | TSHR (0.41) | TSHRNAPRTTDP1SLC6A2SLC6A4 | |
| Pyridine SCHEMBL28104080 | 0.73 | NAPRT (0.41) | TSHRNAPRTTDP1SLC6A2SLC6A4 | |
| Pyridine SCHEMBL28135463 | 0.72 | TSHR (0.36) | TSHRNAPRTTDP1SLC6A2SLC6A4 | |
| Pyridine SCHEMBL28266645 | 0.71 | TSHR (0.39) | TSHRNAPRTTDP1SLC6A2SLC6A4 | |
| Pyridine SCHEMBL28062605 | 0.71 | TSHR (0.39) | TSHRNAPRTTDP1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103288833-B | Imidazo-triazine and imidazopyrimidine as kinase inhibitor | 因塞特控股公司 | 2018-01-12 | — | — | CN | disclosed |