Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 1/20 | 0.54 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylmethanesulfonic Acid SCHEMBL28294303 | 0.95 | CA2 (0.58) | PRSS1PRSS2PRSS3CA1CA2 | |
| Phenylmethanesulfonic Acid SCHEMBL1749 | 0.95 | CA2 (0.58) | PRSS1PRSS2PRSS3CA1CA2 | |
| Phenylmethanesulfonic Acid SCHEMBL127384 | 0.95 | CA2 (0.58) | PRSS1PRSS2PRSS3CA1CA2 | |
| Phenylmethanesulfonic Acid SCHEMBL30217949 | 0.95 | CA2 (0.58) | PRSS1PRSS2PRSS3CA1CA2 | |
| Phenylmethanesulfonic Acid SCHEMBL20543167 | 0.93 | CA2 (0.57) | PRSS1PRSS2PRSS3CA1CA2 | |
| Phenylmethanesulfonic Acid SCHEMBL28859050 | 0.93 | PRSS1 (0.52) | PRSS1PRSS2PRSS3CA1CA2 | |
| Phenylmethanesulfonic Acid SCHEMBL589697 | 0.93 | CA2 (0.56) | PRSS1PRSS2PRSS3CA1CA2 | |
| Phenylmethanesulfonic Acid SCHEMBL9219268 | 0.93 | CA2 (0.56) | PRSS1PRSS2PRSS3CA1CA2 | |
| Phenylmethanesulfonic Acid SCHEMBL1739278 | 0.93 | CA2 (0.56) | PRSS1PRSS2PRSS3CA1CA2 | |
| Phenylmethanesulfonic Acid SCHEMBL21811372 | 0.93 | CA2 (0.56) | PRSS1PRSS2PRSS3CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107693505-A | Double dissolubility ROS sensitive nanoparticles of a kind of new profit and preparation method thereof | 上海长海医院 | 2018-02-16 | — | — | CN | disclosed |
| CN-107551271-A | A kind of dual intelligent targeted nano granules of magnetic ROS and preparation method thereof | 上海长海医院 | 2018-01-09 | — | — | CN | disclosed |