Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2297169 | 0.89 | KDM4E (0.52) | KDM4EMAPTALDH1A1MAPK1PKM | |
| SCHEMBL14312142 | 0.87 | KDM4E (0.51) | KDM4EMAPTALDH1A1MAPK1PKM | |
| SCHEMBL10368118 | 0.82 | DRD4 (0.57) | KDM4EMAPTALDH1A1MAPK1PKM | |
| SCHEMBL20612923 | 0.82 | DRD4 (0.50) | KDM4EMAPTALDH1A1MAPK1PKM | |
| SCHEMBL10365944 | 0.80 | DRD4 (0.61) | KDM4EMAPTALDH1A1MAPK1PKM | |
| SCHEMBL10365995 | 0.80 | DRD4 (0.55) | KDM4EMAPTALDH1A1MAPK1PKM | |
| SCHEMBL10650819 | 0.78 | PKM (0.62) | KDM4EMAPTALDH1A1MAPK1PKM | |
| SCHEMBL16364141 | 0.78 | KDM4E (0.59) | KDM4EMAPTALDH1A1MAPK1PKM | |
| SCHEMBL16106512 | 0.78 | KDM4E (0.41) | KDM4EMAPTALDH1A1PKMKMT2A | |
| SCHEMBL30744755 | 0.78 | KDM4E (0.54) | KDM4EALDH1A1PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105452224-B | Multifunctional quinoline derivatives as anti-neurodegenerative agents | 安基生技新药股份有限公司 | 2017-12-26 | — | — | CN | disclosed |