Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2814893 | 0.93 | TP53 (0.46) | TP53TDP1ALDH1A1CYP3A4MEN1 | |
| SCHEMBL2810015 | 0.89 | TDP1 (0.40) | TP53TDP1ALDH1A1CYP3A4MEN1 | |
| Alachlor SCHEMBL2818223 | 0.89 | TP53 (0.53) | TP53TDP1ALDH1A1CYP3A4MEN1 | |
| Butachlor SCHEMBL2815757 | 0.88 | TDP1 (0.57) | TP53TDP1ALDH1A1CYP3A4MEN1 | |
| SCHEMBL2812407 | 0.87 | TDP1 (0.42) | TP53TDP1ALDH1A1CYP3A4MEN1 | |
| SCHEMBL2808731 | 0.85 | TP53 (0.39) | TP53TDP1ALDH1A1CYP3A4MEN1 | |
| Metolachor SCHEMBL2814388 | 0.85 | ALDH1A1 (0.45) | TP53TDP1ALDH1A1CYP3A4MEN1 | |
| SCHEMBL2812989 | 0.85 | TDP1 (0.43) | TP53TDP1ALDH1A1CYP3A4MEN1 | |
| Pretilachlor SCHEMBL2815535 | 0.84 | NR1I2 (0.56) | TP53TDP1ALDH1A1CYP3A4MEN1 | |
| Dimethachlor SCHEMBL2814025 | 0.83 | TP53 (0.33) | TP53TDP1ALDH1A1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11917994-B2 | Carbamoyl triazolinone based herbicide combinations and method of use | ARYSTA LIFESCIENCE CORPORATION (JP) | 2024-03-05 | — | — | US | disclosed |
| US-11432549-B2 | Carbamoyl triazolinone based herbicide combinations and method of use | ARYSTA LIFESCIENCE CORPORATION (JP) | 2022-09-06 | — | — | US | disclosed |
| US-20200107547-A1 | Carbamoyl Triazolinone Based Herbicide Combinations and Method of Use | ARYSTA LIFESCIENCE CORP (JP) | 2020-04-09 | — | — | US | disclosed |
| US-20190223439-A1 | Carbamoyl Triazolinone Based Herbicide Combinations and Method of Use | ARYSTA LIFESCIENCE CORPORATION (JP) | 2019-07-25 | — | — | US | disclosed |
| US-10299479-B2 | Carbamoyl triazolinone based herbicide combinations and methods of use | ARYSTA LIFESCIENCE CORPORATION (JP) | 2019-05-28 | — | — | US | disclosed |
| EP-3442962-A1 | HERBICIDAL PYRIDAZINONE COMPOUNDS | Syngenta Participations AG (CH) | 2019-02-20 | — | — | EP | disclosed |
| WO-2017178582-A1 | HERBICIDAL PYRIDAZINONE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-10-19 | — | — | WO | disclosed |
| US-20140051579-A1 | CARBAMOYL TRIAZOLINONE BASED HERBICIDE COMBINATIONS AND METHODS OF USE | ARYSTA LIFESCIENCE CORPORATION (JP) | 2014-02-20 | — | — | US | disclosed |
| US-20100311589-A1 | CARBAMOYL TRIAZOLINONE BASED HERBICIDE COMBINATIONS AND METHOD OF USE | ARYSTA LIFESCIENCE CORPORATION (JP) | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11917994-B2 | Carbamoyl triazolinone based herbicide combinations and method of use | DDT, NOTUM, WEE1 | TP53 4299/4885TDP1 2192/4885ALDH1A1 1478/4885 |
| US-20190223439-A1 | Carbamoyl Triazolinone Based Herbicide Combinations and Method of Use | DDT, NOTUM, WEE1 | TP53 4299/4885TDP1 2192/4885ALDH1A1 1478/4885 |
| US-20200107547-A1 | Carbamoyl Triazolinone Based Herbicide Combinations and Method of Use | DDT, NOTUM, WEE1 | TP53 4299/4885TDP1 2192/4885ALDH1A1 1478/4885 |
| US-20140051579-A1 | CARBAMOYL TRIAZOLINONE BASED HERBICIDE COMBINATIONS AND METHODS OF USE | DDT, NOTUM, WEE1 | TP53 4183/4885TDP1 2074/4885ALDH1A1 1367/4885 |
| US-11432549-B2 | Carbamoyl triazolinone based herbicide combinations and method of use | DDT, NOTUM, WEE1 | TP53 4299/4885TDP1 2192/4885ALDH1A1 1478/4885 |
| US-20100311589-A1 | CARBAMOYL TRIAZOLINONE BASED HERBICIDE COMBINATIONS AND METHOD OF USE | DDT, NOTUM, WEE1 | TP53 4299/4885TDP1 2192/4885ALDH1A1 1478/4885 |
| US-10299479-B2 | Carbamoyl triazolinone based herbicide combinations and methods of use | DDT, NOTUM, WEE1 | TP53 4183/4885TDP1 2074/4885ALDH1A1 1367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.