Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952260 | 0.87 | KDM4E (0.50) | KDM4EMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL28195347 | 0.78 | CYP3A4 (0.53) | KDM4EMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL5130608 | 0.75 | MAPT (0.70) | KDM4EMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL20960989 | 0.74 | NPC1 (0.67) | KDM4EMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL28273072 | 0.73 | KMT2A (0.46) | KDM4EMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL17786512 | 0.73 | KDM4E (0.67) | KDM4EMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL17786415 | 0.72 | HSD17B10 (0.74) | KDM4EMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL16332352 | 0.71 | ALDH1A1 (0.51) | KDM4EMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL17786462 | 0.70 | KDM4E (0.70) | KDM4EMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL24182224 | 0.70 | NPC1 (0.66) | KDM4EMAPTALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107635558-A | Bu Luomo domain inhibitor | 赛尔基因昆蒂赛尔研究公司 | 2018-01-26 | — | — | CN | disclosed |