Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17335022 | 0.89 | TDP1 (0.42) | TDP1L3MBTL1ALDH1A1HTTNPSR1 | |
| SCHEMBL24861312 | 0.84 | SMN1; SMN2 (0.49) | TDP1L3MBTL1ALDH1A1HTTNPSR1 | |
| SCHEMBL17335057 | 0.82 | TDP1 (0.62) | TDP1L3MBTL1ALDH1A1HTTNPSR1 | |
| SCHEMBL9833072 | 0.81 | TDP1 (0.45) | TDP1L3MBTL1ALDH1A1HTTMEN1 | |
| SCHEMBL17827834 | 0.81 | TDP1 (0.45) | TDP1L3MBTL1ALDH1A1HTTNPSR1 | |
| SCHEMBL283204 | 0.79 | SMN1; SMN2 (0.42) | TDP1L3MBTL1ALDH1A1HTTNPSR1 | |
| SCHEMBL17334745 | 0.79 | ERN1 (0.51) | TDP1L3MBTL1ALDH1A1HTTNPSR1 | |
| SCHEMBL17336305 | 0.79 | TDP1 (0.65) | TDP1L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL283122 | 0.78 | SMN1; SMN2 (0.43) | TDP1ALDH1A1HTTNPSR1MEN1 | |
| SCHEMBL17335345 | 0.78 | ALDH1A1 (0.43) | TDP1L3MBTL1ALDH1A1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-206823735-U | The synthesis device of 2 ethyoxyl 1 [[(2` itrile groups connect benzene 4 and substituted) methyl] benzimidazole] 7 carboxylate methyl esters | 滨海三甬药业化学有限公司 | 2018-01-02 | — | — | CN | disclosed |