Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12581646 | 0.88 | MAPT (0.52) | MAPTSMN1; SMN2TP53ALDH1A1HTT | |
| SCHEMBL853170 | 0.86 | ALDH1A1 (0.65) | MAPTSMN1; SMN2TP53ALDH1A1HTT | |
| SCHEMBL29722987 | 0.86 | ALDH1A1 (0.65) | MAPTSMN1; SMN2TP53ALDH1A1HTT | |
| SCHEMBL30032841 | 0.83 | TP53 (0.46) | MAPTSMN1; SMN2TP53ALDH1A1HTT | |
| SCHEMBL20374409 | 0.82 | ALDH1A1 (0.49) | MAPTSMN1; SMN2TP53ALDH1A1HTT | |
| SCHEMBL20374353 | 0.82 | ALDH1A1 (0.49) | MAPTSMN1; SMN2TP53ALDH1A1HTT | |
| SCHEMBL78966 | 0.82 | ALDH1A1 (0.56) | MAPTSMN1; SMN2TP53ALDH1A1HTT | |
| SCHEMBL31439294 | 0.81 | MAPT (0.47) | MAPTSMN1; SMN2TP53ALDH1A1HTT | |
| SCHEMBL25586826 | 0.81 | MAPT (0.47) | MAPTSMN1; SMN2TP53ALDH1A1HTT | |
| SCHEMBL10157709 | 0.81 | MAPT (0.47) | MAPTSMN1; SMN2TP53ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107488146-A | ICD derivative and its preparation method and application | 中国科学院兰州化学物理研究所 | 2017-12-19 | — | — | CN | disclosed |