Phenol

Phenol

SCHEMBL28196324

Clc1ccc(Cl)c(Cl)c1.Oc1ccccc1.S

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.61
HSD17B10 Q99714 5/20 0.50
ALDH1A1 P00352 5/20 0.48
TSHR P16473 4/20 0.48
TDP1 Q9NUW8 3/20 0.48
CYP3A4 P08684 2/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
GLA P06280 1/20 0.48
CA3 P07451 1/20 0.48
CA4 P22748 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.42
CASP1 P29466 1/20 0.42
HPGD P15428 2/20 0.40
ALOX15 P16050 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL3238977 0.98 TP53 (0.64) TP53HSD17B10ALDH1A1TSHRTDP1
2,4-Dichlorophenol SCHEMBL2556898 0.83 HSD17B10 (0.74) TP53HSD17B10ALDH1A1TSHRTDP1
Chlorobenzene SCHEMBL15312694 0.81 TP53 (0.74) TP53HSD17B10ALDH1A1TSHRTDP1
Benzene SCHEMBL28277862 0.81 TP53 (0.82) TP53HSD17B10ALDH1A1TSHRTDP1
2,4-Dichlorophenol SCHEMBL28376543 0.81 HSD17B10 (0.71) TP53HSD17B10ALDH1A1TSHRTDP1
Phenol SCHEMBL28085212 0.79 TSHR (0.68) HSD17B10ALDH1A1TSHRTDP1CYP3A4
Phenol SCHEMBL28106636 0.79 TSHR (0.45) TP53HSD17B10ALDH1A1TSHRTDP1
1,4-Dichlorobenzene SCHEMBL28085179 0.79 CA12 (0.61) TSHRTDP1CA12CA1CA2
1,2-Dichlorobenzene SCHEMBL370754 0.78 CA12 (0.69) HSD17B10ALDH1A1TSHRTDP1CYP3A4
1,4-Dichlorobenzene SCHEMBL4557393 0.78 CA12 (0.69) TSHRTDP1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103446724-B Golf 邓禄普体育用品株式会社 2018-01-19 CN disclosed