Phenol

Phenol

SCHEMBL3238977

Clc1ccc(Cl)c(Cl)c1.Oc1ccccc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.64
HSD17B10 Q99714 5/20 0.52
ALDH1A1 P00352 5/20 0.50
TSHR P16473 4/20 0.50
TDP1 Q9NUW8 4/20 0.50
CYP3A4 P08684 2/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
GLA P06280 1/20 0.50
CA3 P07451 1/20 0.50
CA4 P22748 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.43
CASP1 P29466 1/20 0.43
HPGD P15428 2/20 0.41
ALOX15 P16050 2/20 0.41
ALOX12 P18054 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL28196324 0.98 TP53 (0.61) TP53HSD17B10ALDH1A1TSHRTDP1
2,4-Dichlorophenol SCHEMBL2556898 0.84 HSD17B10 (0.74) TP53HSD17B10ALDH1A1TSHRTDP1
Chlorobenzene SCHEMBL15312694 0.83 TP53 (0.74) TP53HSD17B10ALDH1A1TSHRTDP1
Benzene SCHEMBL28277862 0.83 TP53 (0.82) TP53HSD17B10ALDH1A1TSHRTDP1
2,4-Dichlorophenol SCHEMBL28376543 0.83 HSD17B10 (0.71) TP53HSD17B10ALDH1A1TSHRTDP1
Phenol SCHEMBL28106636 0.81 TSHR (0.45) TP53HSD17B10ALDH1A1TSHRTDP1
1,4-Dichlorobenzene SCHEMBL4557393 0.80 CA12 (0.69) TSHRTDP1CA12CA1CA2
1,2-Dichlorobenzene SCHEMBL370754 0.80 CA12 (0.69) HSD17B10ALDH1A1TSHRTDP1CYP3A4
SCHEMBL29349499 0.80
SCHEMBL22730 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109942388-A The preparation method of 1,4- cyclohexanedione 绍兴市上虞沿江生物科技有限公司 2019-06-28 CN disclosed
CN-103788259-B A kind of molecular weight narrow ditribution polypropylene 中国石油化工股份有限公司 2017-05-31 CN disclosed
EP-1170318-B2 Melt processible polyether ether ketone polymer SOLVAY SPECIALITIES INDIA PRIV (IN) 2010-07-28 EP disclosed
EP-1473314-B1 Melt processible polyether ether ketone polymer SOLVAY SPECIALITIES INDIA PRIV (IN) 2009-04-08 EP disclosed
US-6881816-B2 Melt processible polyether ether ketone polymer GHARDA CHEMICALS LTD. (IN) 2005-04-19 US disclosed
EP-1473314-A1 Melt processible polyether ether ketone polymer Gharda Chemicals Limited (IN) 2004-11-03 EP disclosed
EP-1170318-B1 Melt processible polyether ether ketone polymer GHARDA CHEMICALS LTD (IN) 2004-07-21 EP disclosed
US-20030176635-A1 Melt processible polyether ether ketone polymer GHARDA CHEMICALS LTD. 2003-09-18 US disclosed
US-6566484-B2 As useful high temperature engineering and specialty plastics, can be extruded into a rod, film and can also be molded GHARDA CHEMICALS LTD. (IN) 2003-05-20 US disclosed
US-20020040124-A1 Melt processible polyether ether ketone polymer GHARDA CHEMICALS LTD. (IN) 2002-04-04 US disclosed
EP-1170318-A1 Melt processible polyether ether ketone polymer Gharda Chemicals Limited (IN) 2002-01-09 EP disclosed
CN-1185739-A Cyclic peptide fungicides ELI LILLY AD COMPANY (US) 1998-06-24 CN disclosed
US-5175218-A CROSSLINKING POLYMERS WITH COMPOUNDS CONTAINING XANTHENE GROUPS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-12-29 US disclosed
WO-1992006134-A1 CROSSLINKING POLYMERS WITH COMPOUNDS CONTAINING XANTHENE GROUPS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-04-16 WO disclosed