Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 10/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 4/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21711983 | 0.81 | KIF11 (0.46) | KIF11KDM1AFFAR1PDE2A | |
| SCHEMBL701610 | 0.81 | KIF11 (0.46) | KIF11KDM1AFFAR1PDE2A | |
| SCHEMBL4230101 | 0.81 | KIF11 (0.46) | KIF11KDM1AFFAR1PDE2A | |
| SCHEMBL28196872 | 0.81 | KIF11 (0.46) | KIF11KDM1AFFAR1PDE2ATRPM8 | |
| Hydrochloric Acid SCHEMBL25257795 | 0.79 | KIF11 (0.44) | KIF11KDM1ASLC7A5FFAR1PDE2A | |
| Hydrochloric Acid SCHEMBL28665215 | 0.79 | KIF11 (0.44) | KIF11KDM1AFFAR1PDE2A | |
| Hydrochloric Acid SCHEMBL28665216 | 0.79 | KIF11 (0.44) | KIF11KDM1AFFAR1PDE2A | |
| Hydrochloric Acid SCHEMBL14121536 | 0.79 | KIF11 (0.44) | KIF11KDM1AFFAR1PDE2A | |
| SCHEMBL20240221 | 0.79 | PDE2A (0.46) | KIF11KDM1AFFAR1PDE2A | |
| Hydrochloric Acid SCHEMBL14121846 | 0.79 | KIF11 (0.44) | KIF11KDM1AFFAR1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103635472-B | Serine/threonine kinase inhibitor | 阵列生物制药公司 | 2018-01-12 | — | — | CN | disclosed |