SCHEMBL28196643

SCHEMBL28196643

OC(O)Cc1ccncc1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.59
CYP1A2 P05177 2/20 0.59
CYP2C9 P11712 2/20 0.59
CYP2C19 P33261 2/20 0.59
LOXL2 Q9Y4K0 2/20 0.46
SLC6A4 P31645 2/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A3 Q01959 1/20 0.45
ALDH1A1 P00352 2/20 0.44
HSD17B10 Q99714 2/20 0.44
CYP2D6 P10635 1/20 0.44
FDPS P14324 1/20 0.38
HRH1 P35367 2/20 0.37
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
CYP19A1 P11511 1/20 0.36
CHRM1 P11229 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8513064 0.80 CYP3A4 (0.55) CYP3A4CYP1A2CYP2C9CYP2C19LOXL2
SCHEMBL27771941 0.80 CYP3A4 (0.55) CYP3A4CYP1A2CYP2C9CYP2C19LOXL2
SCHEMBL444756 0.80 CYP3A4 (0.55) CYP3A4CYP1A2CYP2C9CYP2C19LOXL2
SCHEMBL2375800 0.80 TAAR1 (0.46) SLC6A4SLC6A2SLC6A3
Hydrochloric Acid SCHEMBL11312932 0.78 CYP3A4 (0.53) CYP3A4CYP1A2CYP2C9CYP2C19LOXL2
SCHEMBL14764141 0.77 CYP3A4 (0.52) CYP3A4CYP1A2CYP2C9CYP2C19LOXL2
SCHEMBL8510037 0.77 CYP3A4 (0.52) CYP3A4CYP1A2CYP2C9CYP2C19LOXL2
SCHEMBL19143563 0.77 CYP3A4 (0.52) CYP3A4CYP1A2CYP2C9CYP2C19LOXL2
SCHEMBL28755663 0.77 CYP3A4 (0.52) CYP3A4CYP1A2CYP2C9CYP2C19LOXL2
SCHEMBL16321985 0.75 TAAR1 (0.60) LOXL2SLC6A4SLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109219438-A The removal of two banks/salt bone 加州大学董事会 2019-01-15 CN disclosed
CN-107667110-A Fluorescence bis-phosphonic acids compounds analog 南加利福尼亚大学 2018-02-06 CN disclosed