Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL27967571 | 0.91 | CYP3A4 (0.44) | CYP3A4CYP1A2CYP2C9CYP2C19LOXL2 | |
| SCHEMBL8510037 | 0.78 | CYP3A4 (0.52) | CYP3A4CYP1A2CYP2C9CYP2C19LOXL2 | |
| SCHEMBL5678777 | 0.77 | EPHX1 (0.52) | CYP1A2LOXL2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1677843 | 0.77 | LOXL2 (0.54) | CYP3A4CYP1A2CYP2C9CYP2C19LOXL2 | |
| SCHEMBL7472546 | 0.77 | EPHX1 (0.52) | CYP1A2LOXL2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL194646 | 0.77 | EPHX1 (0.52) | CYP1A2LOXL2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28196643 | 0.77 | CYP3A4 (0.59) | CYP3A4CYP1A2CYP2C9CYP2C19LOXL2 | |
| SCHEMBL27465388 | 0.76 | LOXL2 (0.48) | CYP3A4CYP1A2CYP2C19LOXL2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7814124 | 0.76 | SRR (0.50) | CYP1A2LOXL2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5007558 | 0.76 | LOXL2 (0.52) | CYP3A4CYP1A2CYP2C9CYP2C19LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2758401-B1 | AMINO-SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER IP GMBH (DE) | 2017-05-31 | — | — | EP | disclosed |
| US-9499547-B2 | Amino-substituted imidazopyridazines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-11-22 | — | — | US | disclosed |
| US-20140296231-A1 | AMINO-SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-02 | — | — | US | disclosed |
| EP-2758401-A1 | AMINO-SUBSTITUTED IMIDAZOPYRIDAZINES | Bayer Intellectual Property GmbH (DE) | 2014-07-30 | — | — | EP | disclosed |
| WO-2013034570-A1 | AMINO-SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296231-A1 | AMINO-SUBSTITUTED IMIDAZOPYRIDAZINES | VEGFA, CCND2, CCND1 | CYP3A4 313/4885CYP1A2 198/4885CYP2C9 868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.