Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 20/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 20/20 | 0.50 |
| ▸ | DRD2 | P14416 | 16/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2819368 | 0.80 | DRD3 (0.68) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL1876340 | 0.74 | DRD3 (0.60) | DRD3KCNH2DRD2CYP1A2 | |
| Hydrochloric Acid SCHEMBL1884183 | 0.74 | DRD3 (0.59) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL2822551 | 0.72 | DRD3 (0.75) | DRD3KCNH2DRD2CYP1A2 | |
| Hydrochloric Acid SCHEMBL2819910 | 0.71 | DRD3 (0.74) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL378256 | 0.71 | DRD3 (0.55) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL13089084 | 0.71 | DRD3 (0.55) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL2819388 | 0.70 | DRD3 (0.54) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL1880957 | 0.69 | DRD3 (0.73) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL1879431 | 0.69 | DRD3 (0.53) | DRD3KCNH2DRD2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891057-B1 | AZABICYCLO[3.1.0]HEXANE DERIVAIVES AS DOPAMIN D3 RECEPTOR MODULATORS | GLAXO GROUP LTD (GB) | 2010-10-27 | — | — | EP | claimed |