Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KLK3 | P07288 | 1/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28197194 | 0.80 | TDP1 (0.46) | KMT2AMEN1ALDH1A1DHODHPOLB | |
| SCHEMBL6080152 | 0.79 | FBP1 (0.49) | KMT2AMEN1AURKAAURKBALDH1A1 | |
| SCHEMBL13313369 | 0.76 | MEN1 (0.60) | KMT2AMEN1ALDH1A1SMN1; SMN2KLK3 | |
| SCHEMBL28823400 | 0.76 | KMT2A (0.60) | KMT2AMEN1ALDH1A1SMN1; SMN2DHODH | |
| SCHEMBL2862878 | 0.75 | MEN1 (0.76) | KMT2AMEN1ALDH1A1SMN1; SMN2KLK3 | |
| SCHEMBL28159695 | 0.74 | TDP1 (0.66) | ALDH1A1DHODHLMNAPOLBRAB9A | |
| SCHEMBL13313368 | 0.72 | KLK3 (0.56) | KMT2AMEN1ALDH1A1SMN1; SMN2KLK3 | |
| SCHEMBL4184403 | 0.72 | KMT2A (0.97) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2862842 | 0.70 | MEN1 (1.00) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13020034 | 0.67 | TDP1 (0.63) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175328-B | It is a kind of using aromatic amine, aromatic aldehyde, ketone synthesis of quinoline derivatives method | 南阳师范学院 | 2017-12-19 | — | — | CN | disclosed |