Questiomycin B

Questiomycin B

SCHEMBL28197880

C1CO1.Nc1ccccc1O

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 6/20 0.75
TSHR P16473 2/20 0.75
SMN1; SMN2 Q16637 5/20 0.43
ALDH1A1 P00352 5/20 0.43
LMNA P02545 4/20 0.43
HSD17B10 Q99714 4/20 0.43
CYP3A4 P08684 3/20 0.43
MAPT P10636 3/20 0.43
HPGD P15428 3/20 0.43
KDM4E B2RXH2 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
NPC1 O15118 1/20 0.43
CA12 O43570 1/20 0.43
GMNN O75496 1/20 0.43
EGFR P00533 1/20 0.43
CA2 P00918 1/20 0.43
FYN P06241 1/20 0.43
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Questiomycin B SCHEMBL24436 0.87
Questiomycin B SCHEMBL29430322 0.87
Questiomycin B SCHEMBL3999786 0.87 ALOX15 (1.00) ALOX15TSHRSMN1; SMN2ALDH1A1LMNA
Questiomycin B SCHEMBL29077530 0.84 ALOX15 (0.83) ALOX15TSHRSMN1; SMN2ALDH1A1LMNA
SCHEMBL18612812 0.84 ALOX15 (0.94) ALOX15TSHRSMN1; SMN2ALDH1A1LMNA
Questiomycin B SCHEMBL3887270 0.84
Questiomycin B SCHEMBL11330404 0.84 ALOX15 (0.94) ALOX15TSHRSMN1; SMN2ALDH1A1LMNA
Questiomycin B SCHEMBL11273511 0.84
Questiomycin B SCHEMBL11412866 0.84
Questiomycin B SCHEMBL31333131 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102819061-B Light guide plate and preparation method thereof 深圳市华星光电技术有限公司 2017-12-29 CN disclosed