Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.44 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.44 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323665 | 0.83 | PTGS2 (0.53) | PTGS1PTGS2PDPK1CYP2C9 | |
| SCHEMBL4830325 | 0.82 | GRN (0.59) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL537395 | 0.80 | PTGS1 (0.65) | PTGS1PTGS2PDPK1CYP1A2KCNJ6 | |
| SCHEMBL7570850 | 0.80 | PTGS1 (0.65) | PTGS1PTGS2PDPK1CYP1A2ALDH1A1 | |
| SCHEMBL31625278 | 0.79 | PDPK1 (0.53) | PTGS1PTGS2PDPK1 | |
| SCHEMBL15478687 | 0.79 | PTGS1 (0.63) | PTGS1PTGS2PDPK1CYP1A2KCNJ6 | |
| SCHEMBL4978131 | 0.79 | PTGS1 (0.63) | PTGS1PTGS2PDPK1CYP1A2KCNJ6 | |
| SCHEMBL4666357 | 0.79 | PTGS1 (0.63) | PTGS1PTGS2PDPK1CYP1A2KCNJ6 | |
| SCHEMBL28157524 | 0.79 | PTGS1 (0.68) | PTGS1PTGS2PDPK1CYP1A2KCNJ6 | |
| SCHEMBL1012734 | 0.79 | PTGS1 (0.63) | PTGS1PTGS2PDPK1CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107567452-A | Imidazopyrazine and pyrazolopyrimidine and their purposes as ampa receptor conditioning agent | 詹森药业有限公司 | 2018-01-09 | — | — | CN | disclosed |