Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.59 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | PAFAH1B2 | P68402 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28757627 | 1.00 | FAAH (0.59) | FAAHLPAR3LPAR2TRPM8MEN1 | |
| SCHEMBL27845158 | 1.00 | FAAH (0.59) | FAAHLPAR3LPAR2TRPM8MEN1 | |
| SCHEMBL27845161 | 1.00 | FAAH (0.59) | FAAHLPAR3LPAR2TRPM8MEN1 | |
| SCHEMBL27540637 | 1.00 | FAAH (0.59) | FAAHLPAR3LPAR2TRPM8MEN1 | |
| SCHEMBL27511510 | 1.00 | FAAH (0.59) | FAAHLPAR3LPAR2TRPM8MEN1 | |
| SCHEMBL28118085 | 0.98 | FAAH (0.56) | FAAHLPAR3LPAR2TRPM8MEN1 | |
| SCHEMBL778284 | 0.90 | — | — | |
| SCHEMBL575263 | 0.86 | FAAH (0.43) | FAAHLPAR3LPAR2TRPM8MEN1 | |
| SCHEMBL25665827 | 0.85 | FAAH (0.46) | FAAHLPAR3LPAR2TRPM8MEN1 | |
| SCHEMBL11294135 | 0.83 | LPAR3 (0.52) | FAAHLPAR3LPAR2TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108291157-A | Selective hydrogenation using flow index | 切弗朗菲利浦化学公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-107667092-A | Formylated N Hete rocyclic derivatives as FGFR4 inhibitor | 诺华股份有限公司 | 2018-02-06 | — | — | CN | disclosed |
| CN-107107049-A | Selective hydrogenation catalyst and its preparation and application | 切弗朗菲利浦化学公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-102341175-B | Selective hydrogenation catalyst and preparation and application thereof | Chevron Phillips Chemical Co.,L.P. (US) | 2016-11-30 | — | — | CN | disclosed |
| CN-102341175-A | Selective hydrogenation catalyst and methods of making and using same | CHEVRON PHILLIPS CHEMICAL CO | 2012-02-01 | — | — | CN | disclosed |