Sulfabenzamide

Sulfabenzamide

SCHEMBL28198214

CC(=O)Nc1ccc(S(N)(=O)=O)cc1.Nc1ccc(S(=O)(=O)NC(=O)c2ccccc2)cc1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.69
KMT2A Q03164 5/20 0.69
LMNA P02545 1/20 0.69
CA1 P00915 9/20 0.61
CA2 P00918 9/20 0.61
CA9 Q16790 8/20 0.61
CA12 O43570 7/20 0.61
PRMT1 Q99873 1/20 0.57
IDO1 P14902 1/20 0.56
CYP2C19 P33261 2/20 0.56
PKM P14618 1/20 0.56
PLK1 P53350 1/20 0.54
MAPT P10636 4/20 0.54
GAA P10253 3/20 0.54
KDM4E B2RXH2 1/20 0.54
ALDH1A1 P00352 1/20 0.54
HPGD P15428 1/20 0.54
CACNA1B Q00975 3/20 0.53
APBA1 Q02410 3/20 0.53
PSMD14 O00487 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9967797 0.89 CA1 (0.64) MEN1KMT2ALMNACA1CA2
Sulfabenzamide SCHEMBL28122269 0.85 MEN1 (0.85) MEN1KMT2ALMNACA1CA2
Sulfabenzamide SCHEMBL93841 0.83 KMT2A (1.00) MEN1KMT2ALMNACA1CA2
Sulfabenzamide SCHEMBL16415986 0.82 KMT2A (0.97) MEN1KMT2ALMNACA1CA2
Sulfabenzamide SCHEMBL28263676 0.81 KMT2A (0.72) MEN1KMT2ALMNACA9CA12
Benzenesulfonamide SCHEMBL11827648 0.80 MEN1 (0.71) MEN1KMT2ALMNACA1CA2
Acetylsulfanilamide SCHEMBL17360801 0.80 CA1 (0.86) MEN1KMT2ACA1CA2CA9
Sulfabenzamide SCHEMBL28121834 0.78 KMT2A (0.83) MEN1KMT2ALMNACA1CA2
SCHEMBL19749350 0.78 MEN1 (0.68) MEN1KMT2ALMNACA1CA2
SCHEMBL27450474 0.78 HSD17B10 (0.71) MEN1KMT2ALMNACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107847505-A MULTILAMELLAR LIPID VESICLE COMPOSITIONS AND METHODS OF USE 威登卓制药公司 2018-03-27 CN disclosed