SCHEMBL28198352

SCHEMBL28198352

C=C(C)C(=O)OCCO.C=CCOC(=O)C=C

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 10/20 0.56
THRB P10828 3/20 0.42
HPGD P15428 1/20 0.40
ALDH1A1 P00352 6/20 0.39
TP53 P04637 3/20 0.39
HIF1A Q16665 3/20 0.39
CYP3A4 P08684 3/20 0.39
HSD17B10 Q99714 1/20 0.39
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MAPT P10636 1/20 0.36
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
TDP1 Q9NUW8 2/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10565297 0.92 THRB (0.50) TSHRTHRBHPGDALDH1A1TP53
SCHEMBL11193751 0.90 THRB (0.47) TSHRTHRBHPGDALDH1A1TP53
SCHEMBL932598 0.90 TSHR (0.70) TSHRTHRBHPGDALDH1A1TP53
SCHEMBL14740570 0.88 TSHR (0.42) TSHRTHRBHPGDALDH1A1TP53
SCHEMBL650597 0.88 TSHR (0.42) TSHRTHRBHPGDALDH1A1TP53
SCHEMBL8212857 0.87 TSHR (0.57) TSHRTHRBHPGDALDH1A1TP53
SCHEMBL28873381 0.87 THRB (0.44) TSHRTHRBALDH1A1CYP3A4HSD17B10
Ethylene SCHEMBL2050495 0.86 TSHR (0.41) TSHRTHRBHPGDALDH1A1TP53
Acrylic Acid Ethyl Ester SCHEMBL5072675 0.85 TSHR (0.58) TSHRTHRBHPGDALDH1A1TP53
Methacrylic Acid SCHEMBL7174132 0.85 THRB (0.43) TSHRTHRBALDH1A1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107614631-A Natural drying type water-based paint compositions 日本油漆株式会社 2018-01-19 CN disclosed