Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1082427 | 0.89 | CYP19A1 (0.35) | ALDH1A1FFAR3 | |
| SCHEMBL1783397 | 0.74 | TSHR (0.44) | ALDH1A1LMNAMAPK1 | |
| SCHEMBL2319822 | 0.71 | ALDH1A1 (0.37) | ALDH1A1LMNAFFAR3 | |
| SCHEMBL8053904 | 0.67 | CYP19A1 (0.39) | — | |
| SCHEMBL11783100 | 0.65 | CYP19A1 (0.31) | THPOHIF1A | |
| SCHEMBL20436278 | 0.64 | — | — | |
| SCHEMBL9509092 | 0.63 | — | — | |
| SCHEMBL8021501 | 0.63 | MAPT (0.43) | ALDH1A1LMNACYP2C19HIF1A | |
| SCHEMBL9959584 | 0.63 | CYP19A1 (0.36) | — | |
| SCHEMBL25076171 | 0.62 | CRBN (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143212-B | Tripeptide epoxy ketone protease inhibitors | 欧尼斯治疗公司 | 2018-02-23 | — | — | CN | disclosed |