Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18920778 | 0.78 | NR4A1 (0.46) | TDP1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL27142066 | 0.76 | CYP1A2 (0.51) | TDP1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL11694319 | 0.76 | TDP1 (0.44) | TDP1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL25415051 | 0.73 | TDP1 (0.67) | TDP1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL7664358 | 0.72 | TDP1 (0.50) | TDP1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL9445878 | 0.72 | RAB9A (0.60) | TDP1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL9445874 | 0.72 | RAB9A (0.60) | TDP1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL7664352 | 0.72 | TDP1 (0.50) | TDP1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL21742339 | 0.71 | TDP1 (0.59) | TDP1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL21742348 | 0.71 | TDP1 (0.59) | TDP1RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107614496-B | Process for preparing aminotetrahydropyran compounds | 意大利合成制造有限公司 | 2020-11-03 | — | — | CN | disclosed |
| CN-107614496-A | The method for preparing amino tetrahydro pyran compound | 意大利合成制造有限公司 | 2018-01-19 | — | — | CN | disclosed |