SCHEMBL28199092

SCHEMBL28199092

CCCCC(=O)Cl.ClP(Cl)Cl

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.84
TP53 P04637 1/20 0.84
TSHR P16473 5/20 0.68
CES1 P23141 6/20 0.50
CES2 O00748 5/20 0.50
CA1 P00915 1/20 0.44
AKR1B1 P15121 1/20 0.40
PPARG P37231 5/20 0.39
PPARD Q03181 5/20 0.39
PPARA Q07869 5/20 0.39
HDAC11 Q96DB2 4/20 0.39
GPR84 Q9NQS5 3/20 0.39
TLR2 O60603 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
FABP4 P15090 2/20 0.39
PTPN1 P18031 2/20 0.39
SLC22A6 Q4U2R8 1/20 0.39
SLC22A8 Q8TCC7 1/20 0.39
MEN1 O00255 1/20 0.39
ESR1 P03372 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3163 0.92
SCHEMBL27570955 0.89
Ammonia Solution, Strong SCHEMBL27949723 0.89
Water SCHEMBL27615437 0.89
SCHEMBL11696114 0.89
Fluoride SCHEMBL27538834 0.89
Methylamine SCHEMBL27769068 0.86 ALDH1A1 (0.89) ALDH1A1TP53TSHRCES1CES2
Methylene Chloride SCHEMBL27667462 0.86 ALDH1A1 (0.89) ALDH1A1TP53TSHRCES1CES2
Acetone SCHEMBL27833869 0.86 ALDH1A1 (0.89) ALDH1A1TP53TSHRCES1CES2
Benzene SCHEMBL27738903 0.84 ALDH1A1 (0.84) ALDH1A1TP53TSHRCES1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107628943-A A kind of preparation method of 5 chlorine valeric chloride 宁波科诺华化工有限公司 2018-01-26 CN disclosed