Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.32 |
| ▸ | RELA | Q04206 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28199159 | 0.77 | NFKB1 (0.40) | NFKB1NFKB2RELA | |
| SCHEMBL28039500 | 0.77 | NFKB1 (0.40) | NFKB1NFKB2RELA | |
| SCHEMBL9836729 | 0.73 | CHRM2 (0.38) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7224503 | 0.68 | — | — | |
| SCHEMBL31472759 | 0.68 | MAPK1 (0.36) | MAPK1 | |
| SCHEMBL2535414 | 0.67 | MAPK1 (0.42) | MAPK1CHRM2CHRM1CHRM3NFKB1 | |
| SCHEMBL8603668 | 0.66 | CHRM2 (0.37) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL28199171 | 0.66 | MAPK1 (0.34) | MAPK1 | |
| SCHEMBL13947268 | 0.64 | NFKB1 (0.37) | MAPK1NFKB1NFKB2RELA | |
| SCHEMBL11227713 | 0.64 | MAPT (0.37) | MAPK1CHRM2CHRM1CHRM3NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143212-B | Tripeptide epoxy ketone protease inhibitors | 欧尼斯治疗公司 | 2018-02-23 | — | — | CN | disclosed |