Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16237346 | 0.87 | KMT2A (0.43) | ALDH1A1GAAMAPTBAZ2BBAZ2A | |
| SCHEMBL22007930 | 0.85 | BAZ2B (0.43) | ALDH1A1GAAMAPTBAZ2BBAZ2A | |
| SCHEMBL16236608 | 0.84 | BAZ2B (0.40) | ALDH1A1GAAMAPTBAZ2BBAZ2A | |
| SCHEMBL22350326 | 0.84 | BAZ2B (0.40) | ALDH1A1GAAMAPTBAZ2BBAZ2A | |
| SCHEMBL22350474 | 0.83 | HSD17B10 (0.38) | ALDH1A1GAACA12CA1CA2 | |
| SCHEMBL22821250 | 0.77 | BAZ2B (0.43) | ALDH1A1GAAMAPTBAZ2BBAZ2A | |
| SCHEMBL22007929 | 0.75 | CA1 (0.48) | ALDH1A1BAZ2BBAZ2ACA12CA1 | |
| SCHEMBL6834500 | 0.75 | ALDH1A1 (0.51) | ALDH1A1GAAMAPTBAZ2BBAZ2A | |
| SCHEMBL3561926 | 0.74 | GAA (0.54) | ALDH1A1GAAMAPTBAZ2BBAZ2A | |
| SCHEMBL21700027 | 0.73 | MAPT (0.40) | ALDH1A1GAAMAPTBAZ2BBAZ2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735400-A | Cyclic sulfamoyl arylamide derivatives and their use as medicaments for the treatment of hepatitis B | 爱尔兰詹森科学公司 | 2018-02-23 | — | — | CN | disclosed |