Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28455111 | 0.75 | TP53 (0.65) | TP53ALDH1A1DAO | |
| SCHEMBL25282861 | 0.73 | TP53 (0.34) | TP53NLRP3 | |
| SCHEMBL28167307 | 0.72 | TP53 (0.39) | TP53 | |
| SCHEMBL12105119 | 0.72 | DAO (0.39) | TP53DAO | |
| SCHEMBL28782010 | 0.72 | HTT (0.39) | TP53ALDH1A1 | |
| SCHEMBL29251607 | 0.71 | TP53 (0.48) | TP53ALDH1A1 | |
| SCHEMBL17706499 | 0.70 | SMN1; SMN2 (0.49) | TP53 | |
| SCHEMBL2079250 | 0.70 | TP53 (0.46) | TP53ALDH1A1 | |
| SCHEMBL15798997 | 0.69 | NPC1 (0.44) | TP53 | |
| SCHEMBL30212716 | 0.69 | TP53 (0.45) | TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107690434-A | Fused tricyclic Imidazopyrazines derivative as TNF active regulators | UCB生物制药私人有限公司 | 2018-02-13 | — | — | CN | disclosed |