Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 3/20 | 0.33 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.32 |
| ▸ | HDAC1 known ✓ | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 known ✓ | Q92769 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27573497 | 0.82 | FFAR3 (0.44) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL18738 | 0.82 | — | — | |
| SCHEMBL6273224 | 0.82 | — | — | |
| Benzene SCHEMBL4101064 | 0.79 | LMNA (0.45) | LMNAMMP1MMP2MMP3MMP8 | |
| Iodide SCHEMBL15299863 | 0.79 | — | — | |
| Ammonia Solution, Strong SCHEMBL28075387 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL668539 | 0.79 | — | — | |
| SCHEMBL27560401 | 0.77 | CHRM1 (0.44) | LMNACHRM1CHRM3AKR1A1HTR2A | |
| Acetic Acid SCHEMBL28859591 | 0.77 | LMNA (0.40) | LMNAMMP1MMP2MMP3MMP8 | |
| Lactic Acid SCHEMBL27520480 | 0.77 | TP53 (0.61) | TP53CHRM1CHRM3AKR1A1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107573242-A | A kind of preparation method of ethyl bromide difluoride | 盐城顺恒化工有限公司 | 2018-01-12 | — | — | CN | claimed |
| CN-107573242-A | A kind of preparation method of ethyl bromide difluoride | 盐城顺恒化工有限公司 | 2018-01-12 | — | — | CN | disclosed |