Acridone

Acridone

SCHEMBL28200023

O=c1c2ccccc2[nH]c2ccccc12.[KH]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.95
KDM4E B2RXH2 5/20 0.95
GAA P10253 3/20 0.95
HTT P42858 3/20 0.95
GLA P06280 2/20 0.95
LMNA P02545 2/20 0.95
HPGD P15428 1/20 0.95
ATM Q13315 1/20 0.95
SMN1; SMN2 Q16637 1/20 0.95
GPR3 P46089 2/20 0.65
HSD17B10 Q99714 2/20 0.65
POLB P06746 4/20 0.64
MEN1 O00255 3/20 0.64
KMT2A Q03164 3/20 0.64
TDP1 Q9NUW8 2/20 0.64
NPC1 O15118 1/20 0.64
CASP6 P55212 1/20 0.64
ABCG2 Q9UNQ0 2/20 0.58
CTSV O60911 1/20 0.56
CTSL P07711 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acridone SCHEMBL29641306 0.97 ALDH1A1 (1.00) ALDH1A1KDM4EGAAHTTGLA
Acridone SCHEMBL29360611 0.97 ALDH1A1 (1.00) ALDH1A1KDM4EGAAHTTGLA
Acridone SCHEMBL19289 0.97 ALDH1A1 (1.00) ALDH1A1KDM4EGAAHTTGLA
Acridone SCHEMBL11519726 0.97 ALDH1A1 (1.00) ALDH1A1KDM4EGAAHTTGLA
Acridone SCHEMBL27512002 0.95 ALDH1A1 (0.95) ALDH1A1KDM4EGAAHTTGLA
Acridone SCHEMBL27589416 0.95 ALDH1A1 (0.95) ALDH1A1KDM4EGAAHTTGLA
Acridone SCHEMBL11523430 0.95 ALDH1A1 (0.95) ALDH1A1KDM4EGAAHTTGLA
Acridone SCHEMBL3420574 0.95 ALDH1A1 (0.95) ALDH1A1KDM4EGAAHTTGLA
SCHEMBL4146783 0.92 ALDH1A1 (0.90) ALDH1A1KDM4EGAAHTTGLA
SCHEMBL30350396 0.92 ALDH1A1 (0.90) ALDH1A1KDM4EGAAHTTGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107694553-A NOxThe manufacture method of occlusion reducing catalyst 丰田自动车株式会社 2018-02-16 CN claimed
CN-107694553-B NOxMethod for producing occluding and reducing catalyst 丰田自动车株式会社 2020-07-03 CN disclosed
CN-107694553-A NOxThe manufacture method of occlusion reducing catalyst 丰田自动车株式会社 2018-02-16 CN disclosed
CN-107694553-A NOxThe manufacture method of occlusion reducing catalyst 丰田自动车株式会社 2018-02-16 CN disclosed