Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28200178 | 0.90 | MAPT (0.50) | MAPTKMT2AALDH1A1MEN1HTT | |
| Sulfuric Acid SCHEMBL28200120 | 0.87 | MAPT (0.49) | MAPTKMT2AALDH1A1MEN1HTT | |
| Phosphoric Acid SCHEMBL28200694 | 0.87 | KCNA5 (0.51) | MAPTKMT2AALDH1A1MEN1HTT | |
| Oxalic Acid SCHEMBL20984276 | 0.80 | MAPT (0.55) | MAPTKMT2AALDH1A1MEN1HTT | |
| Oxalic Acid SCHEMBL20984274 | 0.80 | MAPT (0.55) | MAPTKMT2AALDH1A1MEN1HTT | |
| Oxalic Acid SCHEMBL28200758 | 0.80 | MAPT (0.46) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL28378797 | 0.78 | MAPT (0.57) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL11607569 | 0.77 | PTPN11 (0.71) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL4901069 | 0.76 | MAPT (0.68) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL14042535 | 0.75 | MAPT (0.58) | MAPTKMT2AALDH1A1MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107663161-A | A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt | 上海惠和化德生物科技有限公司 | 2018-02-06 | — | — | CN | disclosed |