Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | IL18 | Q14116 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28200139 | 0.88 | CA2 (0.45) | MAPTLMNATSHRHTTNLRP3 | |
| Sulfuric Acid SCHEMBL28856222 | 0.85 | CA2 (0.50) | MAPTLMNATSHRHTTNLRP3 | |
| Phosphoric Acid SCHEMBL28200771 | 0.85 | MMP2 (0.56) | MAPTLMNATSHRHTTNLRP3 | |
| Oxalic Acid SCHEMBL28374739 | 0.81 | MAPT (0.46) | MAPTLMNATSHRHTTNLRP3 | |
| Oxalic Acid SCHEMBL28200075 | 0.80 | MAPT (0.53) | MAPTLMNATSHRHTTMEN1 | |
| Oxalic Acid SCHEMBL11668337 | 0.79 | CA2 (0.58) | MAPTLMNATSHRHTTNLRP3 | |
| Oxalic Acid SCHEMBL20984921 | 0.77 | IDO1 (0.50) | MAPTLMNATSHRHTTNLRP3 | |
| Oxalic Acid SCHEMBL20984920 | 0.77 | IDO1 (0.50) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL28377566 | 0.75 | MAPT (0.50) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL10037166 | 0.73 | GPR35 (0.67) | MAPTLMNATSHRHTTNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107663161-A | A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt | 上海惠和化德生物科技有限公司 | 2018-02-06 | — | — | CN | disclosed |