Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 2/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2126003 | 0.84 | ALDH1A1 (0.46) | ALDH1A1GLATSHRMEN1KMT2A | |
| Oxalic Acid SCHEMBL28200203 | 0.82 | ALDH1A1 (0.53) | ALDH1A1GLATSHRLMNARAB9A | |
| Hydrochloric Acid SCHEMBL28088635 | 0.82 | ALDH1A1 (0.45) | ALDH1A1GLATSHRMEN1KMT2A | |
| Water SCHEMBL27137011 | 0.82 | ALDH1A1 (0.45) | ALDH1A1GLATSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3130345 | 0.82 | ALDH1A1 (0.45) | ALDH1A1GLATSHRMEN1KMT2A | |
| Phosphoric Acid SCHEMBL28200157 | 0.81 | ALDH1A1 (0.47) | ALDH1A1GLATSHRMEN1KMT2A | |
| Sulfuric Acid SCHEMBL6417780 | 0.81 | ESR1 (0.49) | ALDH1A1GLATSHRS1PR4LMNA | |
| Nitric Acid SCHEMBL28856230 | 0.75 | MEN1 (0.43) | ALDH1A1S1PR4LMNARAB9AMEN1 | |
| Nitric Acid SCHEMBL10995999 | 0.74 | KMT2A (0.58) | ALDH1A1S1PR4LMNARAB9AMEN1 | |
| Nitric Acid SCHEMBL27832818 | 0.74 | HPGD (0.50) | ALDH1A1TSHRS1PR4LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107663161-A | A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt | 上海惠和化德生物科技有限公司 | 2018-02-06 | — | — | CN | disclosed |