Toluene

Toluene

SCHEMBL28200424

Cc1ccccc1.O=C1CCC(=O)O1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
LMNA P02545 1/20 0.52
ALOX12 P18054 1/20 0.52
ACHE P22303 1/20 0.52
HPGD P15428 3/20 0.40
KDM4E B2RXH2 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
GLA P06280 1/20 0.40
SIRT1 Q96EB6 1/20 0.40
HSD17B10 Q99714 1/20 0.40
ALDH1A1 P00352 2/20 0.38
ALDH2 P05091 1/20 0.38
CTRB1 P17538 1/20 0.37
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
MEN1 O00255 1/20 0.36
POLB P06746 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29074500 0.77 ACHE (0.56) TSHRLMNAACHEMEN1KMT2A
Naphthalene SCHEMBL27718735 0.77 TSHR (0.61) TSHRLMNAALOX12HPGDKDM4E
SCHEMBL27492584 0.76 TSHR (0.52) TSHRHPGDKDM4ECYP1A2CYP2C9
Aniline SCHEMBL9867186 0.76 TSHR (0.52) TSHRALOX12HPGDKDM4ECYP1A2
Phenol SCHEMBL27268997 0.76 GLA (0.52) TSHRHPGDKDM4ECYP1A2CYP2C9
SCHEMBL29190731 0.75 TSHR (0.58) TSHRHPGDKDM4ECYP1A2CYP2C9
SCHEMBL31510121 0.75 TSHR (0.58) TSHRHPGDKDM4ECYP1A2CYP2C9
Benzene SCHEMBL14673229 0.75 TSHR (0.58) TSHRLMNAHPGDKDM4ECYP1A2
Phthalic Anhydride SCHEMBL8372249 0.73 TDP1 (0.70) TSHRLMNAALOX12ACHEHPGD
Toluene SCHEMBL7662176 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118027580-A Thermo-oxidative aging resistant PVC (polyvinyl chloride) sizing material and preparation method thereof 广东银豪塑胶制品有限公司 2024-05-14 CN claimed
CN-118027580-A Thermo-oxidative aging resistant PVC (polyvinyl chloride) sizing material and preparation method thereof 广东银豪塑胶制品有限公司 2024-05-14 CN disclosed
CN-115684104-A Shigella rapid detection method based on up-conversion-gold nano fluorescence resonance energy transfer 南京农业大学 2023-02-03 CN disclosed
CN-111171301-B Preparation method and application of nitrogenous copolymerized polylactic acid 东华大学 2021-04-06 CN disclosed
CN-111171301-A Preparation method and application of nitrogenous copolymerized polylactic acid 东华大学 2020-05-19 CN disclosed
CN-107759600-A Crystallization as the Pyrrolopyrimidine compounds of JAK inhibitor 正大天晴药业集团股份有限公司 2018-03-06 CN disclosed