Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL6931516 | 1.00 | THRB (0.35) | THRBTSHRALDH1A1LMNATDP1 | |
| Boric Acid SCHEMBL28285073 | 0.88 | THRB (0.43) | THRBTSHRALDH1A1LMNATDP1 | |
| Boric Acid SCHEMBL4976220 | 0.88 | THRB (0.43) | THRBTSHRALDH1A1LMNATDP1 | |
| Boric Acid SCHEMBL4139673 | 0.88 | THRB (0.43) | THRBTSHRALDH1A1LMNATDP1 | |
| Boric Acid SCHEMBL594481 | 0.88 | THRB (0.43) | THRBTSHRALDH1A1LMNATDP1 | |
| Boric Acid SCHEMBL474845 | 0.88 | THRB (0.43) | THRBTSHRALDH1A1LMNATDP1 | |
| Boric Acid SCHEMBL17962526 | 0.88 | THRB (0.43) | THRBTSHRALDH1A1LMNATDP1 | |
| Benzene SCHEMBL27835884 | 0.88 | THRB (0.43) | THRBTSHRALDH1A1 | |
| Boric Acid SCHEMBL28230424 | 0.84 | THRB (0.40) | THRBTSHRALDH1A1LMNATDP1 | |
| Boric Acid SCHEMBL28207524 | 0.84 | THRB (0.40) | THRBTSHRALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105461720-B | Morpholine class tyrosine kinase inhibitor | 南京圣和药业股份有限公司 | 2019-08-06 | — | — | CN | disclosed |
| CN-109824691-A | Liquid-crystal compounds and its preparation based on cyclopentadiene 1,4-Dithiapentalene -4- ketone | 四川师范大学 | 2019-05-31 | — | — | CN | disclosed |
| CN-105683183-B | The pyridine being substituted-piperazinyl analog as RSV antiviral compounds | 爱尔兰詹森科学公司 | 2018-06-22 | — | — | CN | disclosed |
| CN-107540574-A | The preparation method of R biphenyl Propanolamines | 成都西岭源药业有限公司 | 2018-01-05 | — | — | CN | disclosed |