Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 14/20 | 0.63 |
| ▸ | BTK | Q06187 | 11/20 | 0.59 |
| ▸ | LCK | P06239 | 10/20 | 0.59 |
| ▸ | EGFR | P00533 | 5/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18283500 | 0.87 | JAK3 (0.81) | JAK3BTKLCKEGFR | |
| SCHEMBL20540783 | 0.87 | JAK3 (0.81) | JAK3BTKLCKEGFR | |
| SCHEMBL16763718 | 0.77 | JAK3 (1.00) | JAK3BTKLCKEGFR | |
| SCHEMBL16763984 | 0.77 | JAK3 (1.00) | JAK3BTKLCKEGFR | |
| SCHEMBL28323995 | 0.77 | BTK (0.64) | JAK3BTKLCKEGFR | |
| SCHEMBL23081127 | 0.76 | JAK3 (0.81) | JAK3BTKLCKEGFR | |
| SCHEMBL16764351 | 0.74 | BTK (1.00) | JAK3BTKLCKEGFR | |
| SCHEMBL16764515 | 0.74 | BTK (1.00) | JAK3BTKLCKEGFR | |
| SCHEMBL22346055 | 0.74 | JAK3 (0.62) | JAK3BTKLCKEGFR | |
| SCHEMBL22346054 | 0.74 | JAK3 (0.62) | JAK3BTKLCKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709315-A | The inhibitor of bruton's tyrosine kinase | 药品循环有限责任公司 | 2018-02-16 | — | — | CN | disclosed |