Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 1/20 | 0.43 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28455222 | 0.78 | LMNA (0.53) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL18681826 | 0.77 | MAPT (0.44) | MAPTCYP2C19CTSVCTSLCTSB | |
| SCHEMBL24190480 | 0.76 | CYP1A2 (0.46) | MAPTCYP2C19CTSVCTSLCTSB | |
| SCHEMBL29015434 | 0.76 | CYP1A2 (0.46) | MAPTCYP2C19CTSVCTSLCTSB | |
| SCHEMBL10120775 | 0.75 | LMNA (0.43) | MAPTCYP2C19CTSVCTSLCTSB | |
| SCHEMBL20107268 | 0.74 | PSEN1 (0.49) | MAPTCYP2C19CTSVCTSLCTSB | |
| SCHEMBL14428886 | 0.72 | SMYD2 (0.37) | MAPTCYP2C19CTSVCTSLCTSB | |
| SCHEMBL19231385 | 0.72 | LMNA (0.43) | MAPTCYP2C19CTSVCTSLCTSB | |
| SCHEMBL27726515 | 0.71 | FASN (0.45) | — | |
| SCHEMBL524084 | 0.71 | LMNA (0.58) | CTSVCTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112661736-B | Synthetic method of tylosin intermediate | 广州市力鑫药业有限公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-112661736-A | Synthetic method of tylosin intermediate | 广州市力鑫药业有限公司 | 2021-04-16 | — | — | CN | disclosed |
| CN-107709332-A | A kind of C, O loop coil aryl glycoside class compound and its preparation and application | 中国科学院上海药物研究所 | 2018-02-16 | — | — | CN | disclosed |