SCHEMBL28200728

SCHEMBL28200728

Fc1ccc(F)cc1.NNC(=O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
IDO1 P14902 1/20 0.42
BCL2L1 Q07817 1/20 0.41
BAD Q92934 1/20 0.41
KCNN4 O15554 3/20 0.40
PTPN1 P18031 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
MITF O75030 1/20 0.38
CTBP2 P56545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27625470 0.82 ALDH1A1 (0.50) ALDH1A1CES2CES1IDO1BCL2L1
SCHEMBL241697 0.79
Hydrochloric Acid SCHEMBL28332228 0.76
Hydrochloric Acid SCHEMBL11594970 0.76
SCHEMBL28970660 0.76
SCHEMBL27525354 0.76
SCHEMBL2200065 0.74 PTPN1 (0.61) ALDH1A1PTPN1NPC1RAB9AMITF
Oxalic Acid SCHEMBL20984258 0.74 ALDH1A1 (0.54) ALDH1A1IDO1PTPN1NPC1RAB9A
Fluorobenzene SCHEMBL27604330 0.73 KCNN4 (0.45) ALDH1A1KCNN4NPC1RAB9A
SCHEMBL20711477 0.73 GAA (0.54) ALDH1A1IDO1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107663161-A A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt 上海惠和化德生物科技有限公司 2018-02-06 CN disclosed