SCHEMBL28201154

SCHEMBL28201154

C=CCOC(=O)C=C.C=Cc1ccc(C=C)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.51
CYP3A4 P08684 3/20 0.47
SNCA P37840 1/20 0.44
ALDH1A1 P00352 6/20 0.42
THRB P10828 1/20 0.42
TSHR P16473 6/20 0.41
HSD17B10 Q99714 2/20 0.41
TP53 P04637 3/20 0.41
HIF1A Q16665 3/20 0.41
MAPT P10636 2/20 0.41
CACNA1B Q00975 1/20 0.41
APBA1 Q02410 1/20 0.41
TDP1 Q9NUW8 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
MAPK1 P28482 2/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL167641 0.91 CYP3A4 (0.51) APPCYP3A4SNCAALDH1A1THRB
Styrene SCHEMBL3117319 0.88 CYP3A4 (0.49) APPCYP3A4SNCAALDH1A1THRB
Styrene SCHEMBL10818757 0.85 CYP3A4 (0.46) APPCYP3A4ALDH1A1THRBTSHR
SCHEMBL31267242 0.83 TSHR (0.54) APPCYP3A4SNCAALDH1A1THRB
SCHEMBL19273 0.83
SCHEMBL5167665 0.83 TSHR (0.54) APPCYP3A4SNCAALDH1A1THRB
Styrene SCHEMBL8097534 0.83 MEN1 (0.47) APPCYP3A4ALDH1A1THRBTSHR
Styrene SCHEMBL5613413 0.83 CYP3A4 (0.44) APPCYP3A4ALDH1A1THRBTSHR
Styrene SCHEMBL9654658 0.83 CYP3A4 (0.44) APPCYP3A4ALDH1A1THRBTSHR
SCHEMBL3680375 0.81 CYP3A4 (0.53) APPCYP3A4ALDH1A1THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108699170-A Thermoformable polymer/fiber composite material 巴斯夫欧洲公司 2018-10-23 CN claimed
CN-108699170-A Thermoformable polymer/fiber composite material 巴斯夫欧洲公司 2018-10-23 CN disclosed
CN-107643558-A Band is laminated with the optical film of the adhesive phase of barrier film 住友化学株式会社 2018-01-30 CN disclosed