Propene

Propene

SCHEMBL28201402

C=CC.CCCC(C#N)C(=O)O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.40
AKR1A1 P14550 1/20 0.40
CHRM3 P20309 1/20 0.40
HTR2A P28223 1/20 0.40
HTR2C P28335 1/20 0.40
ADRA1A P35348 1/20 0.40
HRH1 P35367 1/20 0.40
DRD3 P35462 1/20 0.40
SLC6A3 Q01959 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
GRIK1 P39086 1/20 0.32
SLC1A3 P43003 1/20 0.32
SLC1A2 P43004 1/20 0.32
SLC1A1 P43005 1/20 0.32
GRIK2 Q13002 1/20 0.32
CA2 P00918 1/20 0.31
MAPK1 P28482 1/20 0.31
GPR84 Q9NQS5 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL651947 0.90
SCHEMBL10494055 0.90
SCHEMBL10494014 0.90
Ammonia Solution, Strong SCHEMBL27495500 0.88 CHRM1 (0.46) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL27372501 0.88 CHRM1 (0.46) CHRM1AKR1A1CHRM3HTR2AHTR2C
Propane SCHEMBL29178080 0.88 CHRM1 (0.46) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL28958900 0.88 CHRM1 (0.46) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL27899488 0.83 CHRM1 (0.39) CHRM1AKR1A1CHRM3HTR2AHTR2C
Propene SCHEMBL4543717 0.78 TDP1 (0.34) TDP1GRIK1GRIK2
SCHEMBL316535 0.78 CA2 (0.48) CHRM1AKR1A1CHRM3HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105555806-B Medical or beast medical apparatus surface modification 新加坡国立大学 2018-04-10 CN disclosed