Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL136875 | 0.83 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28866107 | 0.82 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28228982 | 0.81 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16537856 | 0.79 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL23923099 | 0.78 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16537216 | 0.78 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL21066699 | 0.78 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1024055 | 0.78 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL26918769 | 0.78 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL137795 | 0.77 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107698766-A | Curable compositions, method, purposes and the device of side chain polysiloxane and correlation | 道康宁公司 | 2018-02-16 | — | — | CN | disclosed |