Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21066699 | 1.00 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL23923099 | 1.00 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16537216 | 1.00 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL26918769 | 1.00 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16537856 | 0.98 | TSHR (0.53) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL136875 | 0.94 | TSHR (0.50) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL28866107 | 0.92 | TSHR (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL65597 | 0.87 | THRB (0.46) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16537548 | 0.86 | TSHR (0.58) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL21066734 | 0.86 | TSHR (0.58) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3669854-B1 | PHOTOPOLYMERIZABLE DENTAL COMPOSITION | G C DENTAL IND CORP (JP) | 2026-04-08 | — | — | EP | disclosed |
| WO-2025126917-A1 | DENTAL COMPOSITION | クラレノリタケデンタル株式会社 | 2025-06-19 | — | — | WO | disclosed |
| EP-3373887-B1 | KIT OF PARTS FOR PRODUCING A GLASS IONOMER CEMENT, PROCESS OF PRODUCTION AND USE THEREOF | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-11-27 | — | — | EP | disclosed |
| EP-3586814-B1 | DENTAL CURABLE COMPOSITION | G C DENTAL IND CORP (JP) | 2024-01-31 | — | — | EP | disclosed |
| US-20220313564-A1 | DENTAL RESTORATION COMPOSITE RESIN | GC CORPORATION (JP) | 2022-10-06 | — | — | US | disclosed |
| US-11446214-B2 | Curable dental composite | GC CORPORATION (JP) | 2022-09-20 | — | — | US | disclosed |
| EP-4018993-A1 | DENTAL RESTORATION COMPOSITE RESIN | GC Corporation (JP) | 2022-06-29 | — | — | EP | disclosed |
| CN-113677309-A | Two-component curable dental composition | 株式会社GC | 2021-11-19 | — | — | CN | disclosed |
| US-11135138-B2 | Self-adhesive dental resin composition and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2021-10-05 | — | — | US | disclosed |
| US-11135137-B2 | Dental photopolymerizable composition | GC CORPORATION (JP) | 2021-10-05 | — | — | US | disclosed |
| EP-2123247-B1 | CURABLE COMPOSITION FOR DENTAL PURPOSES | KURARAY NORITAKE DENTAL INC (JP) | 2016-08-17 | — | — | EP | disclosed |
| US-20150320646-A1 | DENTAL CURABLE COMPOSITION AND DENTAL FLOWABLE COMPOSITE RESIN | KURARAY NORITAKE DENTAL INC. (JP) | 2015-11-12 | — | — | US | disclosed |
| EP-2926796-A1 | DENTAL CURABLE COMPOSITION AND DENTAL FLOWABLE COMPOSITE RESIN | Kuraray Noritake Dental Inc. (JP) | 2015-10-07 | — | — | EP | disclosed |
| CN-104797232-A | Dental curable composition and dental flowable composite resin | KURARAY NORITAKE DENTAL INC | 2015-07-22 | — | — | CN | disclosed |
| US-8455564-B2 | Dental composition and composite resin | KURARAY NORITAKE DENTAL INC. (JP) | 2013-06-04 | — | — | US | disclosed |
| US-7951851-B2 | Curable composition for dental purposes | KURARAY MEDICAL INC. (JP) | 2011-05-31 | — | — | US | disclosed |
| US-20110046261-A1 | DENTAL COMPOSITION AND COMPOSITE RESIN | KURARAY MEDICAL INC. (JP) | 2011-02-24 | — | — | US | disclosed |
| EP-2275076-A1 | DENTAL COMPOSITION AND COMPOSITE RESIN | Kuraray Medical Inc. (JP) | 2011-01-19 | — | — | EP | disclosed |
| US-20100105802-A1 | CURABLE COMPOSITION FOR DENTAL PURPOSES | KURARAY MEDICAL INC. (JP) | 2010-04-29 | — | — | US | disclosed |
| EP-2123247-A1 | CURABLE COMPOSITION FOR DENTAL PURPOSES | Kuraray Medical Inc. (JP) | 2009-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105802-A1 | CURABLE COMPOSITION FOR DENTAL PURPOSES | H1-0, H1-3, H1-2 | TSHR 2517/4885POLB 696/4885APEX1 1834/4885 |
| US-20220313564-A1 | DENTAL RESTORATION COMPOSITE RESIN | ARCN1, COG1, SEM1 | TSHR 3773/4885POLB 772/4885APEX1 2102/4885 |
| US-11135137-B2 | Dental photopolymerizable composition | ALAD, HTT, PPA1 | TSHR 2336/4885POLB 950/4885APEX1 844/4885 |
| US-20110046261-A1 | DENTAL COMPOSITION AND COMPOSITE RESIN | CAD, KATNAL2, ZYX | TSHR 3309/4885POLB 623/4885APEX1 4096/4885 |
| US-11135138-B2 | Self-adhesive dental resin composition and use thereof | ORAI1, CACNA1E, TBCA | TSHR 3456/4885POLB 1653/4885APEX1 938/4885 |
| US-11446214-B2 | Curable dental composite | VCL, CORO1A, ACTB | TSHR 3573/4885POLB 588/4885APEX1 3501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.