Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACA | Q13085 | 4/20 | 0.68 |
| ▸ | AURKA | O14965 | 1/20 | 0.57 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ACP1 | P24666 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18698086 | 0.89 | KDM4E (0.52) | ACACAMAPTTP53KDM4EALDH1A1 | |
| SCHEMBL13458889 | 0.87 | ACACA (0.73) | ACACAAURKAAURKBMAPTKDM4E | |
| SCHEMBL3704468 | 0.87 | ACACA (0.73) | ACACAAURKAAURKBMAPTKDM4E | |
| SCHEMBL13458687 | 0.86 | ACACA (0.71) | ACACAAURKAAURKBMAPTKDM4E | |
| SCHEMBL13458951 | 0.86 | ACACA (0.71) | ACACAAURKAAURKBMAPTKDM4E | |
| SCHEMBL28201471 | 0.83 | TOP1 (0.53) | ACACAKDM4ELMNAHPGDHTT | |
| SCHEMBL29726805 | 0.81 | ACACA (1.00) | ACACAAURKAAURKBMAPTKDM4E | |
| SCHEMBL25522200 | 0.81 | ACACA (1.00) | ACACAAURKAAURKBMAPTKDM4E | |
| SCHEMBL16295684 | 0.81 | ACACA (1.00) | ACACAAURKAAURKBMAPTKDM4E | |
| SCHEMBL25181505 | 0.80 | ACACA (0.97) | ACACAAURKAAURKBMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107739333-B | A kind of preparation method of the quinoline compound of green | 大连理工大学 | 2019-09-27 | — | — | CN | disclosed |
| CN-107739333-A | A kind of preparation method of green quinoline compound | 大连理工大学 | 2018-02-27 | — | — | CN | disclosed |