SCHEMBL28201496

SCHEMBL28201496

CCS(=O)(=O)OC1CCC(OC)CC1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
HCRTR2 O43614 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14778289 0.91 CA1 (0.37) CA1CA2
SCHEMBL14779150 0.91
SCHEMBL28143306 0.85 ENPP3 (0.30)
SCHEMBL28286254 0.82 KDM4E (0.33) CA1CA2HCRTR2
SCHEMBL20576086 0.82
SCHEMBL14779982 0.81 CA1 (0.44) CA1CA2
SCHEMBL14779778 0.81 GRIN1 (0.31) CA1CA2
SCHEMBL778390 0.81 CA1 (0.50) CA1CA2
SCHEMBL4132677 0.80 CA1 (0.31) CA1CA2
SCHEMBL14779532 0.79 CA1 (0.54) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107614501-B Hydroxyl purine compound and application thereof 广东众生睿创生物科技有限公司 2020-01-14 CN disclosed
CN-106715438-B Triazolopyrazine ketone as PDE1 inhibitor H.隆德贝克有限公司 2019-04-12 CN disclosed
CN-107614501-A Hydroxyl purine compound and application thereof 广东众生药业股份有限公司 2018-01-19 CN disclosed