Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14463486 | 0.88 | — | — | |
| Water SCHEMBL28293448 | 0.85 | — | — | |
| SCHEMBL17484301 | 0.79 | — | — | |
| SCHEMBL83428 | 0.78 | — | — | |
| SCHEMBL11473535 | 0.73 | — | — | |
| 1,3-Propanediol SCHEMBL28186723 | 0.71 | — | — | |
| 1,4-Butanediol SCHEMBL5702839 | 0.71 | TSHR (0.58) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL15285802 | 0.71 | DNM1 (0.50) | ALDH1A1TSHR | |
| SCHEMBL28660655 | 0.71 | — | — | |
| SCHEMBL11472619 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107652836-A | Performances of Novel Nano-Porous silicon protective coating, city integrated piping lane pre-buried channel flow and support | 合肥卡勒斯通建筑材料有限公司 | 2018-02-02 | — | — | CN | disclosed |