SCHEMBL28201602

SCHEMBL28201602

COC(=O)CNCOC(C)=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.48
MGAM O43451 2/20 0.48
SI P14410 2/20 0.48
MGAM2 Q2M2H8 2/20 0.48
TSHR P16473 6/20 0.40
TET2 Q6N021 1/20 0.40
ALDH1A1 P00352 5/20 0.39
RECQL P46063 1/20 0.39
HSD17B10 Q99714 3/20 0.39
LMNA P02545 1/20 0.39
PGR P06401 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
HTR1A P08908 1/20 0.32
CHRM5 P08912 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRNB2 P17787 1/20 0.32
CHRM3 P20309 1/20 0.32
TBXA2R P21731 1/20 0.32
CHRNB4 P30926 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20444223 0.83 ALDH1A1 (0.43) GAAMGAMSIMGAM2TSHR
SCHEMBL24890617 0.80 GAA (0.41) GAAMGAMSIMGAM2TSHR
SCHEMBL66336 0.80 ALDH1A1 (0.50) GAAMGAMSIMGAM2TSHR
SCHEMBL21173246 0.78 ALDH1A1 (0.40) GAAMGAMSIMGAM2TSHR
SCHEMBL18307349 0.78
SCHEMBL12329903 0.78 GAA (0.55) GAAMGAMSIMGAM2TSHR
SCHEMBL18975313 0.78 TOP2A (0.33) GAAMGAMSIMGAM2
SCHEMBL73416 0.77 TSHR (0.56) GAAMGAMSIMGAM2TSHR
Hydrochloric Acid SCHEMBL112927 0.75 TSHR (0.53) GAAMGAMSIMGAM2TSHR
SCHEMBL15865613 0.74 GAA (0.50) GAAMGAMSIMGAM2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108463466-A Glycolipid compounds and their use in the treatment of tumors 艾佳尔免疫有限公司 2018-08-28 CN disclosed
CN-107735404-A Multivalent ligand-lipid constructs 尼古拉·弗拉基米罗维奇·鲍文 2018-02-23 CN disclosed