Acrylic Acid Methyl Ester

Acrylic Acid Methyl Ester

SCHEMBL28201902

C=C(C)C(=O)OC.C=CC(=O)OC.[CH2]C

nearest known ligand 0.65

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Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.65
HCAR2 Q8TDS4 2/20 0.39
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
TSHR P16473 10/20 0.38
HPGD P15428 1/20 0.32
TP53 P04637 3/20 0.32
THRB P10828 1/20 0.31
HIF1A Q16665 2/20 0.31
CYP3A4 P08684 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Methyl Ester SCHEMBL4172054 0.98 ALDH1A1 (0.68) ALDH1A1HCAR2KEAP1NFE2L2TSHR
Acrylic Acid Methyl Ester SCHEMBL2936703 0.98 ALDH1A1 (0.68) ALDH1A1HCAR2KEAP1NFE2L2TSHR
Acrylic Acid Methyl Ester SCHEMBL138017 0.98 ALDH1A1 (0.68) ALDH1A1HCAR2KEAP1NFE2L2TSHR
Acrylic Acid Methyl Ester SCHEMBL7212877 0.98 ALDH1A1 (0.68) ALDH1A1HCAR2KEAP1NFE2L2TSHR
Acrylic Acid Methyl Ester SCHEMBL4171350 0.98 ALDH1A1 (0.68) ALDH1A1HCAR2KEAP1NFE2L2TSHR
Acrylic Acid Methyl Ester SCHEMBL4163868 0.98 ALDH1A1 (0.68) ALDH1A1HCAR2KEAP1NFE2L2TSHR
Acrylic Acid Methyl Ester SCHEMBL5706532 0.98 ALDH1A1 (0.68) ALDH1A1HCAR2KEAP1NFE2L2TSHR
Acrylic Acid Methyl Ester SCHEMBL29246453 0.98 ALDH1A1 (0.68) ALDH1A1HCAR2KEAP1NFE2L2TSHR
Acrylic Acid Methyl Ester SCHEMBL30909403 0.96 ALDH1A1 (0.65) ALDH1A1HCAR2KEAP1NFE2L2TSHR
Acrylic Acid Methyl Ester SCHEMBL28084091 0.96 ALDH1A1 (0.65) ALDH1A1HCAR2KEAP1NFE2L2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107698766-A Curable compositions, method, purposes and the device of side chain polysiloxane and correlation 道康宁公司 2018-02-16 CN disclosed